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Combinatorial interplay of RNA-binding proteins tunes levels of mitochondrial mRNA in trypanosomes

MRP1/2 is a heteromeric protein complex that functions in the trypanosomatid mitochondrion as part of the RNA editing machinery, which facilitates multiple targeted insertions and deletions of uridines. MRP1/2 was shown to interact with MRB8170, which initiates RNA editing by marking pre-edited mRNA...

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Detalles Bibliográficos
Autores principales: Dixit, Sameer, Lukeš, Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191715/
https://www.ncbi.nlm.nih.gov/pubmed/30120147
http://dx.doi.org/10.1261/rna.066233.118