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Direct quantification of 3′ terminal 2′-O-methylation of small RNAs by RT-qPCR
Modification of nucleotides significantly increases the diversity of functional nucleic acids. As one of the most common modifications of RNAs, methylation of the 2′-hydroxyl-group of ribonucleotides (2′-O-methylation) has been found in various RNAs in eukaryotes. However, due to the lack of an effi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191718/ https://www.ncbi.nlm.nih.gov/pubmed/30076204 http://dx.doi.org/10.1261/rna.065144.117 |