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SCN5A Variants: Association With Cardiac Disorders
The SCN5A gene encodes the alpha subunit of the main cardiac sodium channel Na(v)1.5. This channel predominates inward sodium current (INa) and plays a critical role in regulation of cardiac electrophysiological function. Since 1995, SCN5A variants have been found to be causatively associated with B...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191725/ https://www.ncbi.nlm.nih.gov/pubmed/30364184 http://dx.doi.org/10.3389/fphys.2018.01372 |