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SCN5A Variants: Association With Cardiac Disorders

The SCN5A gene encodes the alpha subunit of the main cardiac sodium channel Na(v)1.5. This channel predominates inward sodium current (INa) and plays a critical role in regulation of cardiac electrophysiological function. Since 1995, SCN5A variants have been found to be causatively associated with B...

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Detalles Bibliográficos
Autores principales: Li, Wenjia, Yin, Lei, Shen, Cheng, Hu, Kai, Ge, Junbo, Sun, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191725/
https://www.ncbi.nlm.nih.gov/pubmed/30364184
http://dx.doi.org/10.3389/fphys.2018.01372