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Lung Perfusion Imaging in Tetralogy of Fallot: A Case Report

Congenital heart diseases, such as tetralogy of fallot (TOF), are the most common human birth defects that may cause pulmonary diseases. Lung perfusion scintigraphy (LPS) has an important role in evaluating pulmonary involvement in patients with these defects, both as part of the diagnostic work-up...

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Autores principales: Asabella, Artor Niccoli, Cimino, Alessandra, Altini, Corinna, Lavelli, Valentina, Rubini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191732/
https://www.ncbi.nlm.nih.gov/pubmed/30317856
http://dx.doi.org/10.4274/mirt.04909
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author Asabella, Artor Niccoli
Cimino, Alessandra
Altini, Corinna
Lavelli, Valentina
Rubini, Giuseppe
author_facet Asabella, Artor Niccoli
Cimino, Alessandra
Altini, Corinna
Lavelli, Valentina
Rubini, Giuseppe
author_sort Asabella, Artor Niccoli
collection PubMed
description Congenital heart diseases, such as tetralogy of fallot (TOF), are the most common human birth defects that may cause pulmonary diseases. Lung perfusion scintigraphy (LPS) has an important role in evaluating pulmonary involvement in patients with these defects, both as part of the diagnostic work-up and for follow-up to guide best therapeutic strategy. Herein, we report a 10-year-old female patient with TOF who underwent LPS two years after cardiac surgery. The scan showed hypo-perfusion of the left respect to the right lung and abnormal uptake of Tc-99m-macroaggregated albumin in the kidneys and spleen, revealing the presence of a right-to-left shunt, and the necessity for further cardiac surgery. This case is a demonstrative example of the usefulness of LPS in patients with TOF, allowing an accurate evaluation of the best therapeutic strategy with the benefits of low radiation exposure, lack of side effects, reproducibility, management ease and good patient compliance.
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spelling pubmed-61917322018-10-22 Lung Perfusion Imaging in Tetralogy of Fallot: A Case Report Asabella, Artor Niccoli Cimino, Alessandra Altini, Corinna Lavelli, Valentina Rubini, Giuseppe Mol Imaging Radionucl Ther Interesting Image Congenital heart diseases, such as tetralogy of fallot (TOF), are the most common human birth defects that may cause pulmonary diseases. Lung perfusion scintigraphy (LPS) has an important role in evaluating pulmonary involvement in patients with these defects, both as part of the diagnostic work-up and for follow-up to guide best therapeutic strategy. Herein, we report a 10-year-old female patient with TOF who underwent LPS two years after cardiac surgery. The scan showed hypo-perfusion of the left respect to the right lung and abnormal uptake of Tc-99m-macroaggregated albumin in the kidneys and spleen, revealing the presence of a right-to-left shunt, and the necessity for further cardiac surgery. This case is a demonstrative example of the usefulness of LPS in patients with TOF, allowing an accurate evaluation of the best therapeutic strategy with the benefits of low radiation exposure, lack of side effects, reproducibility, management ease and good patient compliance. Galenos Publishing 2018-10 2018-10-09 /pmc/articles/PMC6191732/ /pubmed/30317856 http://dx.doi.org/10.4274/mirt.04909 Text en ©Copyright 2018 by Turkish Society of Nuclear Medicine / Molecular Imaging and Radionuclide Therapy published by Galenos Yayinevi. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Interesting Image
Asabella, Artor Niccoli
Cimino, Alessandra
Altini, Corinna
Lavelli, Valentina
Rubini, Giuseppe
Lung Perfusion Imaging in Tetralogy of Fallot: A Case Report
title Lung Perfusion Imaging in Tetralogy of Fallot: A Case Report
title_full Lung Perfusion Imaging in Tetralogy of Fallot: A Case Report
title_fullStr Lung Perfusion Imaging in Tetralogy of Fallot: A Case Report
title_full_unstemmed Lung Perfusion Imaging in Tetralogy of Fallot: A Case Report
title_short Lung Perfusion Imaging in Tetralogy of Fallot: A Case Report
title_sort lung perfusion imaging in tetralogy of fallot: a case report
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191732/
https://www.ncbi.nlm.nih.gov/pubmed/30317856
http://dx.doi.org/10.4274/mirt.04909
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