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Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on (18)F-FDG PET/CT

A 43-year-old male patient presented with a mass lesion on the right liver lobe, segment 5, in radiological imaging and elevated alpha-fetoprotein levels (323 ng/mL) compatible with hepatocellular carcinoma (HCC). Positron emission tomography/computed tomography (PET/CT) images showed background lev...

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Autores principales: Erdoğan, Ezgi Başak, Türk, Hacı Mehmet, Tekçe, Ertuğrul, Aydın, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191735/
https://www.ncbi.nlm.nih.gov/pubmed/30317851
http://dx.doi.org/10.4274/mirt.93723
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author Erdoğan, Ezgi Başak
Türk, Hacı Mehmet
Tekçe, Ertuğrul
Aydın, Mehmet
author_facet Erdoğan, Ezgi Başak
Türk, Hacı Mehmet
Tekçe, Ertuğrul
Aydın, Mehmet
author_sort Erdoğan, Ezgi Başak
collection PubMed
description A 43-year-old male patient presented with a mass lesion on the right liver lobe, segment 5, in radiological imaging and elevated alpha-fetoprotein levels (323 ng/mL) compatible with hepatocellular carcinoma (HCC). Positron emission tomography/computed tomography (PET/CT) images showed background level (18)F-FDG uptake in the mass lesion. In addition, a secondary focus of increased (18)F-FDG uptake was detected on the left liver lobe, segment 2, approximately 1,5 cm in diameter. Histopathological examination revealed HCC in the larger mass lesion with a lower (18)F-FDG uptake, and cholangiocellular carcinoma in the smaller mass lesion with a higher (18)F-FDG uptake. To our knowledge, this is the first case report of two histopathologically different primary malignant liver tumors in two distinct segments of the liver detected by PET/CT.
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spelling pubmed-61917352018-10-22 Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on (18)F-FDG PET/CT Erdoğan, Ezgi Başak Türk, Hacı Mehmet Tekçe, Ertuğrul Aydın, Mehmet Mol Imaging Radionucl Ther Interesting Image A 43-year-old male patient presented with a mass lesion on the right liver lobe, segment 5, in radiological imaging and elevated alpha-fetoprotein levels (323 ng/mL) compatible with hepatocellular carcinoma (HCC). Positron emission tomography/computed tomography (PET/CT) images showed background level (18)F-FDG uptake in the mass lesion. In addition, a secondary focus of increased (18)F-FDG uptake was detected on the left liver lobe, segment 2, approximately 1,5 cm in diameter. Histopathological examination revealed HCC in the larger mass lesion with a lower (18)F-FDG uptake, and cholangiocellular carcinoma in the smaller mass lesion with a higher (18)F-FDG uptake. To our knowledge, this is the first case report of two histopathologically different primary malignant liver tumors in two distinct segments of the liver detected by PET/CT. Galenos Publishing 2018-10 2018-10-09 /pmc/articles/PMC6191735/ /pubmed/30317851 http://dx.doi.org/10.4274/mirt.93723 Text en ©Copyright 2018 by Turkish Society of Nuclear Medicine / Molecular Imaging and Radionuclide Therapy published by Galenos Yayinevi. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Interesting Image
Erdoğan, Ezgi Başak
Türk, Hacı Mehmet
Tekçe, Ertuğrul
Aydın, Mehmet
Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on (18)F-FDG PET/CT
title Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on (18)F-FDG PET/CT
title_full Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on (18)F-FDG PET/CT
title_fullStr Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on (18)F-FDG PET/CT
title_full_unstemmed Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on (18)F-FDG PET/CT
title_short Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on (18)F-FDG PET/CT
title_sort synchronous hepatocellular carcinoma and cholangiocellular carcinoma on (18)f-fdg pet/ct
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191735/
https://www.ncbi.nlm.nih.gov/pubmed/30317851
http://dx.doi.org/10.4274/mirt.93723
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