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TRPV2-induced Ca(2+)-calcineurin-NFAT signaling regulates differentiation of osteoclast in multiple myeloma
BACKGROUND: Myeloma bone disease (MBD) can cause bone destruction and increase the level of Ca(2+) concentration in the bone marrow microenvironment by stimulating osteoclastic differentiation. Nevertheless, the relationships between MBD and highly efficient stimuli of Ca(2+) in multiple myeloma (MM...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191893/ https://www.ncbi.nlm.nih.gov/pubmed/30326911 http://dx.doi.org/10.1186/s12964-018-0280-8 |