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TRPV2-induced Ca(2+)-calcineurin-NFAT signaling regulates differentiation of osteoclast in multiple myeloma

BACKGROUND: Myeloma bone disease (MBD) can cause bone destruction and increase the level of Ca(2+) concentration in the bone marrow microenvironment by stimulating osteoclastic differentiation. Nevertheless, the relationships between MBD and highly efficient stimuli of Ca(2+) in multiple myeloma (MM...

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Detalles Bibliográficos
Autores principales:	Bai, Hua, Zhu, Huayuan, Yan, Qing, Shen, Xuxing, Lu, Xiupan, Wang, Juejin, Li, Jianyong, Chen, Lijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191893/ https://www.ncbi.nlm.nih.gov/pubmed/30326911 http://dx.doi.org/10.1186/s12964-018-0280-8

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