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High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model

Hemoglobin-based oxygen carriers (HBOCs) are an investigational replacement for blood transfusions and are known to cause oxidative damage to tissues. To investigate the correlation between their oxygen binding properties and these detrimental effects, we investigated two PEGylated HBOCs endowed wit...

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Detalles Bibliográficos
Autores principales:	Alomari, Esra'a, Ronda, Luca, Bruno, Stefano, Paredi, Gianluca, Marchetti, Marialaura, Bettati, Stefano, Olivari, Davide, Fumagalli, Francesca, Novelli, Deborah, Ristagno, Giuseppe, Latini, Roberto, Cooper, Chris E., Reeder, Brandon J., Mozzarelli, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191936/ https://www.ncbi.nlm.nih.gov/pubmed/29920341 http://dx.doi.org/10.1016/j.freeradbiomed.2018.06.018

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