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AFF3 upregulation mediates tamoxifen resistance in breast cancers
BACKGROUND: Although tamoxifen is a highly effective drug for treating estrogen receptor–positive (ER(+)) breast cancer, nearly all patients with metastasis with initially responsive tumors eventually relapse, and die from acquired drug resistance. Unfortunately, few molecular mediators of tamoxifen...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192118/ https://www.ncbi.nlm.nih.gov/pubmed/30326937 http://dx.doi.org/10.1186/s13046-018-0928-7 |