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Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

BACKGROUND: Mitochondrial dysfunction has been implicated in the pathologies of a number of retinal degenerative diseases in both the outer and inner retina. In the outer retina, photoreceptors are particularly vulnerable to mutations affecting mitochondrial function due to their high energy demand...

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Detalles Bibliográficos
Autores principales:	Kiyama, Takae, Chen, Ching-Kang, Wang, Steven W, Pan, Ping, Ju, Zhenlin, Wang, Jing, Takada, Shinako, Klein, William H, Mao, Chai-An
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192121/ https://www.ncbi.nlm.nih.gov/pubmed/30333037 http://dx.doi.org/10.1186/s13024-018-0287-z

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