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Impaired GABA Neural Circuits Are Critical for Fragile X Syndrome

Fragile X syndrome (FXS) is an inheritable neuropsychological disease caused by silence of the fmr1 gene and the deficiency of Fragile X mental retardation protein (FMRP). Patients present neuronal alterations that lead to severe intellectual disability and altered sleep rhythms. However, the neural...

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Detalles Bibliográficos
Autores principales: Gao, Fei, Qi, Lijun, Yang, Zhongzhen, Yang, Tao, Zhang, Yan, Xu, Hui, Zhao, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192167/
https://www.ncbi.nlm.nih.gov/pubmed/30402088
http://dx.doi.org/10.1155/2018/8423420