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Simulating the dynamics of targeted capture sequencing with CapSim
MOTIVATION: Targeted sequencing using capture probes has become increasingly popular in clinical applications due to its scalability and cost-effectiveness. The approach also allows for higher sequencing coverage of the targeted regions resulting in better analysis statistical power. However, becaus...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192212/ https://www.ncbi.nlm.nih.gov/pubmed/29092025 http://dx.doi.org/10.1093/bioinformatics/btx691 |