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CLDN2 inhibits the metastasis of osteosarcoma cells via down-regulating the afadin/ERK signaling pathway

BACKGROUND: In an earlier study, we investigated the expression of tight junction protein claudins (CLDNs) in human osteosarcoma (OS) cells, and the CLDN2 was found to be down-regulated in primary tumor cells compared with normal osteoblast cells. Here, we sought to explore the effects of CLDN2 on t...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaowei, Wang, Haiming, Li, Qian, Li, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192349/ https://www.ncbi.nlm.nih.gov/pubmed/30349422 http://dx.doi.org/10.1186/s12935-018-0662-4

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