Oxidative stress in sperm affects the epigenetic reprogramming in early embryonic development

BACKGROUND: Reactive oxygen species (ROS)-induced oxidative stress is well known to play a major role in male infertility. Sperm are sensitive to ROS damaging effects because as male germ cells form mature sperm they progressively lose the ability to repair DNA damage. However, how oxidative DNA les...

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Detalles Bibliográficos
Autores principales: Wyck, Sarah, Herrera, Carolina, Requena, Cristina E., Bittner, Lilli, Hajkova, Petra, Bollwein, Heinrich, Santoro, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192351/
https://www.ncbi.nlm.nih.gov/pubmed/30333056
http://dx.doi.org/10.1186/s13072-018-0224-y

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