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Comparison of Quantitative and Qualitative (Q)SAR Models Created for the Prediction of K(i) and IC(50) Values of Antitarget Inhibitors

Estimation of interaction of drug-like compounds with antitargets is important for the assessment of possible toxic effects during drug development. Publicly available online databases provide data on the experimental results of chemical interactions with antitargets, which can be used for the creat...

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Detalles Bibliográficos
Autores principales:	Lagunin, Alexey A., Romanova, Maria A., Zadorozhny, Anton D., Kurilenko, Natalia S., Shilov, Boris V., Pogodin, Pavel V., Ivanov, Sergey M., Filimonov, Dmitry A., Poroikov, Vladimir V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192375/ https://www.ncbi.nlm.nih.gov/pubmed/30364128 http://dx.doi.org/10.3389/fphar.2018.01136

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