An autopsy report of three kindred in a Gerstmann–Sträussler–Scheinker disease P105L family with a special reference to prion protein, tau, and beta‐amyloid

INTRODUCTION: Gerstmann–Sträussler–Scheinker disease P105L (GSS105) is a rare variant of GSS caused by a point mutation of the prion protein (PrP) gene at codon 105 (proline to leucine substitution). It is clinically characterized by spastic paraparesis and dementia and histopathologically defined b...

Descripción completa

Detalles Bibliográficos
Autores principales: Ishizawa, Keisuke, Mitsufuji, Takashi, Shioda, Kei, Kobayashi, Atsushi, Komori, Takashi, Nakazato, Yoshihiko, Kitamoto, Tetsuyuki, Araki, Nobuo, Yamamoto, Toshimasa, Sasaki, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192393/
https://www.ncbi.nlm.nih.gov/pubmed/30240140
http://dx.doi.org/10.1002/brb3.1117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192393/
https://www.ncbi.nlm.nih.gov/pubmed/30240140
http://dx.doi.org/10.1002/brb3.1117

Ejemplares similares