Cargando…
In vitro toxicity and efficacy of verdinexor, an exportin 1 inhibitor, on opportunistic viruses affecting immunocompromised individuals
Infection of immunocompromised individuals with normally benign opportunistic viruses is a major health burden globally. Infections with viruses such as Epstein-Barr virus (EBV), human cytomegalovirus (HCMV), Kaposi’s sarcoma virus (KSHV), adenoviruses (AdV), BK virus (BKPyV), John Cunningham virus...
Autores principales: | Widman, Douglas G., Gornisiewicz, Savanna, Shacham, Sharon, Tamir, Sharon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192554/ https://www.ncbi.nlm.nih.gov/pubmed/30332435 http://dx.doi.org/10.1371/journal.pone.0200043 |
Ejemplares similares
-
Antiviral Efficacy of Verdinexor In Vivo in Two Animal Models of Influenza A Virus Infection
por: Perwitasari, Olivia, et al.
Publicado: (2016) -
Verdinexor, a Selective Inhibitor of Nuclear Exportin 1, Inhibits the Proliferation and Migration of Esophageal Cancer via XPO1/c-Myc/FOSL1 Axis
por: Ou, Ling, et al.
Publicado: (2022) -
Specific Inhibition of the Nuclear Exporter Exportin-1 Attenuates Kidney Cancer Growth
por: Wettersten, Hiromi I., et al.
Publicado: (2014) -
Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma
por: Boons, Eline, et al.
Publicado: (2015) -
A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export (SINE) compounds
por: Crochiere, Marsha L., et al.
Publicado: (2015)