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Nanotracing and cavity-ring down spectroscopy: A new ultrasensitive approach in large molecule drug disposition studies

New therapeutic biological entities such as bispecific antibodies targeting tissue or specific cell populations form an increasingly important part of the drug development portfolio. However, these biopharmaceutical agents bear the risk of extensive target-mediated drug disposition or atypical pharm...

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Detalles Bibliográficos
Autores principales: Kratochwil, Nicole A., Dueker, Stephen R., Muri, Dieter, Senn, Claudia, Yoon, HyeJin, Yu, Byung-Yong, Lee, Gwan-Ho, Dong, Feng, Otteneder, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192596/
https://www.ncbi.nlm.nih.gov/pubmed/30332475
http://dx.doi.org/10.1371/journal.pone.0205435