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Nanotracing and cavity-ring down spectroscopy: A new ultrasensitive approach in large molecule drug disposition studies
New therapeutic biological entities such as bispecific antibodies targeting tissue or specific cell populations form an increasingly important part of the drug development portfolio. However, these biopharmaceutical agents bear the risk of extensive target-mediated drug disposition or atypical pharm...
Autores principales: | Kratochwil, Nicole A., Dueker, Stephen R., Muri, Dieter, Senn, Claudia, Yoon, HyeJin, Yu, Byung-Yong, Lee, Gwan-Ho, Dong, Feng, Otteneder, Michael B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192596/ https://www.ncbi.nlm.nih.gov/pubmed/30332475 http://dx.doi.org/10.1371/journal.pone.0205435 |
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