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A methyl-sensitive element induces bidirectional transcription in TATA-less CpG island-associated promoters

How TATA-less promoters such as those within CpG islands (CGI) control gene expression is still a subject of active research. Here, we have identified the “CGCG element”, a ten-base pair motif with a consensus sequence of TCTCGCGAGA present in a group of promoter-associated CGI-enriched in ribosomal...

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Detalles Bibliográficos
Autores principales: Mahpour, Amin, Scruggs, Benjamin S., Smiraglia, Dominic, Ouchi, Toru, Gelman, Irwin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192621/
https://www.ncbi.nlm.nih.gov/pubmed/30332484
http://dx.doi.org/10.1371/journal.pone.0205608

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