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A methyl-sensitive element induces bidirectional transcription in TATA-less CpG island-associated promoters
How TATA-less promoters such as those within CpG islands (CGI) control gene expression is still a subject of active research. Here, we have identified the “CGCG element”, a ten-base pair motif with a consensus sequence of TCTCGCGAGA present in a group of promoter-associated CGI-enriched in ribosomal...
Autores principales: | Mahpour, Amin, Scruggs, Benjamin S., Smiraglia, Dominic, Ouchi, Toru, Gelman, Irwin H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192621/ https://www.ncbi.nlm.nih.gov/pubmed/30332484 http://dx.doi.org/10.1371/journal.pone.0205608 |
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