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A most wanted list of conserved microbial protein families with no known domains

The number and proportion of genes with no known function are growing rapidly. To quantify this phenomenon and provide criteria for prioritizing genes for functional characterization, we developed a bioinformatics pipeline that identifies robustly defined protein families with no annotated domains,...

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Detalles Bibliográficos
Autores principales: Wyman, Stacia K., Avila-Herrera, Aram, Nayfach, Stephen, Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192648/
https://www.ncbi.nlm.nih.gov/pubmed/30332487
http://dx.doi.org/10.1371/journal.pone.0205749