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An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse
Tobacco use disorder is the leading cause of disease and preventable death worldwide, but current medications that are based on pharmacodynamics have low efficacy. Novel pharmacokinetic approaches to prevent nicotine from reaching the brain have been tested using vaccines, but these efforts have fai...
Autores principales: | Kallupi, Marsida, Xue, Song, Zhou, Bin, Janda, Kim D., George, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192681/ https://www.ncbi.nlm.nih.gov/pubmed/30345354 http://dx.doi.org/10.1126/sciadv.aat4751 |
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