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An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse

Tobacco use disorder is the leading cause of disease and preventable death worldwide, but current medications that are based on pharmacodynamics have low efficacy. Novel pharmacokinetic approaches to prevent nicotine from reaching the brain have been tested using vaccines, but these efforts have fai...

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Detalles Bibliográficos
Autores principales: Kallupi, Marsida, Xue, Song, Zhou, Bin, Janda, Kim D., George, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192681/
https://www.ncbi.nlm.nih.gov/pubmed/30345354
http://dx.doi.org/10.1126/sciadv.aat4751

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