Prevention of pesticide-induced neuronal dysfunction and mortality with nucleophilic poly-Oxime topical gel

Organophosphate-based pesticides inhibit acetylcholinesterase (AChE), which plays a pivotal role in neuromuscular function. While spraying in the field, farmworkers get exposed to pesticides through the dermal route. Internalized pesticide inhibits AChE, which leads to neurotoxicity, cardiotoxicity,...

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Detalles Bibliográficos
Autores principales: Thorat, Ketan, Pandey, Subhashini, Chandrashekharappa, Sandeep, Vavilthota, Nikitha, Hiwale, Ankita A., Shah, Purna, Sreekumar, Sneha, Upadhyay, Shubhangi, Phuntsok, Tenzin, Mahato, Manohar, Mudnakudu-Nagaraju, Kiran K., Sunnapu, Omprakash, Vemula, Praveen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192682/
https://www.ncbi.nlm.nih.gov/pubmed/30345360
http://dx.doi.org/10.1126/sciadv.aau1780

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