Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation

On the basis of population genomic and phylogeographic analyses of 1669 Mycobacterium tuberculosis lineage 4 (L4) genomes, we find that dispersal of L4 has been completely dominated by historical migrations out of Europe. We demonstrate an intimate temporal relationship between European colonial exp...

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Detalles Bibliográficos
Autores principales: Brynildsrud, Ola B., Pepperell, Caitlin S., Suffys, Philip, Grandjean, Louis, Monteserin, Johana, Debech, Nadia, Bohlin, Jon, Alfsnes, Kristian, Pettersson, John O.-H., Kirkeleite, Ingerid, Fandinho, Fatima, da Silva, Marcia Aparecida, Perdigao, Joao, Portugal, Isabel, Viveiros, Miguel, Clark, Taane, Caws, Maxine, Dunstan, Sarah, Thai, Phan Vuong Khac, Lopez, Beatriz, Ritacco, Viviana, Kitchen, Andrew, Brown, Tyler S., van Soolingen, Dick, O’Neill, Mary B., Holt, Kathryn E., Feil, Edward J., Mathema, Barun, Balloux, Francois, Eldholm, Vegard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192687/
https://www.ncbi.nlm.nih.gov/pubmed/30345355
http://dx.doi.org/10.1126/sciadv.aat5869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192687/
https://www.ncbi.nlm.nih.gov/pubmed/30345355
http://dx.doi.org/10.1126/sciadv.aat5869

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