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Identification of potential biomarkers in cholestasis and the therapeutic effect of melatonin by metabolomics, multivariate data and pathway analyses

The present study investigated the anti-cholestatic effect of melatonin (MT) against α-naphthyl isothiocyanate (ANIT)-induced liver injury in rats and screened for potential biomarkers of cholestasis. Rats were administered ANIT by intraperitoneal injection and then sacrificed 36 h later. Serum bioc...

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Detalles Bibliográficos
Autores principales: Yu, Han, Li, Yunzhou, Xu, Zongying, Wang, Dingnan, Shi, Shaohua, Deng, Huifang, Zeng, Baihui, Zheng, Zhili, Sun, Lili, Deng, Xiulan, Zhong, Xianggen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192756/
https://www.ncbi.nlm.nih.gov/pubmed/30226547
http://dx.doi.org/10.3892/ijmm.2018.3859