Cargando…

Pterostilbene inhibits nutrient metabolism and induces apoptosis through AMPK activation in multiple myeloma cells

Multiple myeloma (MM) cells are characterized by an abnormal nutrient metabolism that is distinct from normal plasma cells. Pterostilbene (PTE), a bioactive component of blueberries, has been demonstrated to induce apoptosis in multiple types of cancer cell. The present study evaluated whether PTE t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mei, Huiling, Xiang, Yu, Mei, Heng, Fang, Bin, Wang, Qiuguo, Cao, Dedong, Hu, Yu, Guo, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192759/ https://www.ncbi.nlm.nih.gov/pubmed/30226553 http://dx.doi.org/10.3892/ijmm.2018.3857

Ejemplares similares

Pterostilbene Inhibits Human Multiple Myeloma Cells via ERK1/2 and JNK Pathway In Vitro and In Vivo
por: Xie, Bingqian, et al.
Publicado: (2016)

Anticancer Activity of Pterostilbene in Human Ovarian Cancer Cell Lines
por: Pei, Hui-lin, et al.
Publicado: (2017)

Pterostilbene promotes mitochondrial apoptosis and inhibits proliferation in glioma cells
por: Gao, Haijun, et al.
Publicado: (2021)

Potential Chemopreventive Role of Pterostilbene in Its Modulation of the Apoptosis Pathway
por: Surien, Omchit, et al.
Publicado: (2023)

Effect of pterostilbene on in vitro drug metabolizing enzyme activity
por: Albassam, Ahmed A., et al.
Publicado: (2019)

Pterostilbene in Cancer Therapy
por: Obrador, Elena, et al.
Publicado: (2021)

Pterostilbene induces apoptosis in hepatocellular carcinoma cells: Biochemical, pathological, and molecular markers
por: Khalil, Mahmoud I., et al.
Publicado: (2023)

Pterostilbene induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma cells
por: Kong, Yuanyuan, et al.
Publicado: (2016)

Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer
por: Chen, Rong-Jane, et al.
Publicado: (2018)

New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects
por: Nagarajan, Sanjushree, et al.
Publicado: (2022)

Pterostilbene suppresses oxidative stress and allergic airway inflammation through AMPK/Sirt1 and Nrf2/HO‐1 pathways
por: Xu, Chang, et al.
Publicado: (2021)

Pterostilbene protects cochlea from ototoxicity in streptozotocin-induced diabetic rats by inhibiting apoptosis
por: Özdaş, Sibel, et al.
Publicado: (2020)

Oral Delivery of Pterostilbene by L-Arginine-Mediated “Nano-Bomb” Carrier for the Treatment of Ulcerative Colitis
por: Wei, Wei, et al.
Publicado: (2022)

Pterostilbene Activates the Nrf2-Dependent Antioxidant Response to Ameliorate Arsenic-Induced Intracellular Damage and Apoptosis in Human Keratinocytes
por: Zhou, Junfeng, et al.
Publicado: (2019)

Multiple Mechanisms Converging on Transcription Factor EB Activation by the Natural Phenol Pterostilbene
por: La Spina, Martina, et al.
Publicado: (2021)

Pterostilbene Fails to Rescue Insulin Secretion and Sensitivity in Multiple Murine Models of Diabetes
por: Damgaard, Mads V., et al.
Publicado: (2022)

AMPK – roles in nutrient sensing and in cancer
por: Hardie, D Grahame
Publicado: (2014)

Effect of Magnesium Ion on the Radical-Scavenging Rate of Pterostilbene in an Aprotic Medium: Mechanistic Insight into the Antioxidative Reaction of Pterostilbene
por: Nakanishi, Ikuo, et al.
Publicado: (2022)

Pterostilbene on Metabolic Parameters: A Randomized, Double-Blind, and Placebo-Controlled Trial
por: Riche, Daniel M., et al.
Publicado: (2014)

Biological actions and molecular effects of resveratrol, pterostilbene, and 3′-hydroxypterostilbene
por: Tsai, Hui-Yun, et al.
Publicado: (2016)

Synthesis and antiproliferative activity of pterostilbene and [Formula: see text] -methoxy pterostilbene Mannich base derivatives against Hela cells
por: Liu, Chongyang, et al.
Publicado: (2015)

Adipocytes secreted leptin is a pro-tumor factor for survival of multiple myeloma under chemotherapy
por: Yu, Wen, et al.
Publicado: (2016)

PGC1α activation by pterostilbene ameliorates acute doxorubicin cardiotoxicity by reducing oxidative stress via enhancing AMPK and SIRT1 cascades
por: Liu, Dong, et al.
Publicado: (2019)

The Structure-Activity Relationship of Pterostilbene Against Candida albicans Biofilms
por: Hu, Dan-Dan, et al.
Publicado: (2017)

Cytotoxicity Studies of Novel Combretastatin and Pterostilbene Derivatives
por: Jakubowska, Joanna, et al.
Publicado: (2014)

Case-specific potentiation of glioblastoma drugs by pterostilbene
por: Schmidt, Linnéa, et al.
Publicado: (2016)

Case Report: ITP Treatment After CAR-T Cell Therapy in Patients With Multiple Myeloma
por: Du, Mengyi, et al.
Publicado: (2022)

Correction: Adipocytes secreted leptin is a pro-tumor factor for survival of multiple myeloma under chemotherapy
por: Yu, Wen, et al.
Publicado: (2023)

Pterostilbene inhibits lung squamous cell carcinoma growth in vitro and in vivo by inducing S phase arrest and apoptosis
por: Tan, Kok-Tong, et al.
Publicado: (2019)

Pterostilbene Induces Cell Apoptosis and Cell Cycle Arrest in T-Cell Leukemia/Lymphoma by Suppressing the ERK1/2 Pathway
por: Chang, Gaomei, et al.
Publicado: (2017)

Pterostilbene reduces endothelial cell injury in vascular arterial walls by regulating the Nrf2-mediated AMPK/STAT3 pathway in an atherosclerosis rat model
por: Tang, Tieyu, et al.
Publicado: (2020)

Components of metabolic syndrome in patients with multiple myeloma and smoldering multiple myeloma
por: Markus, Efrat, et al.
Publicado: (2020)

Modulation of macrophage polarization and lung cancer cell stemness by MUC1 and development of a related small-molecule inhibitor pterostilbene
por: Huang, Wen-Chien, et al.
Publicado: (2016)

Metabolic Features of Multiple Myeloma
por: El Arfani, Chaima, et al.
Publicado: (2018)

Metabolic Disorders in Multiple Myeloma
por: Gavriatopoulou, Maria, et al.
Publicado: (2021)

Metabolic Vulnerabilities in Multiple Myeloma
por: Lim, Julia S. L., et al.
Publicado: (2022)

Determinants of Sensitivity to DZNep Induced Apoptosis in Multiple Myeloma Cells
por: Xie, Zhigang, et al.
Publicado: (2011)

Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages
por: Ma, Chuanrui, et al.
Publicado: (2021)

Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway
por: Xue, En-Xing, et al.
Publicado: (2017)

Modulation of Innate Immune Toxicity by Silver Nanoparticle Exposure and the Preventive Effects of Pterostilbene
por: Chen, Rong-Jane, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_e7prd9c70i02poi7iucbrsoh6r