Overexpression of SENP1 reduces the stemness capacity of osteosarcoma stem cells and increases their sensitivity to HSVtk/GCV

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Osteosarcoma stem cells are able to escape treatment with conventional chemotherapeutic drugs, as the majority of them are in a quiescent state. Recent reports have suggested that small ubiquitin-like modifiers (SUMOs) serve important roles in the maintenance of cancer stem cell stemness. Therefore,...

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Detalles Bibliográficos
Autores principales: Liu, Fengting, Li, Lili, Li, Yanxia, Ma, Xiaofang, Bian, Xiyun, Liu, Xiaozhi, Wang, Guowen, Zhang, Dianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192779/
https://www.ncbi.nlm.nih.gov/pubmed/30226577
http://dx.doi.org/10.3892/ijo.2018.4537
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