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Opening of mitoK(ATP) improves cardiac function and inhibits apoptosis via the AKT-Foxo1 signaling pathway in diabetic cardiomyopathy

Decreasing phosphorylation of AKT-Foxo1 is closely associated with the onset of insulin resistance and apoptosis during diabetic cardiomyopathy (DCM). Opening of mitochondrial ATP-sensitive potassium channels (mitoK(ATP)) increases the expression of p-AKT in the process of reperfusion injury. It was...

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Detalles Bibliográficos
Autores principales:	Duan, Peng, Wang, Jinxin, Li, Yang, Wei, Shiqiang, Su, Feng, Zhang, Sanlin, Duan, Yuhui, Wang, Lin, Zhu, Qinglei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192784/ https://www.ncbi.nlm.nih.gov/pubmed/30132505 http://dx.doi.org/10.3892/ijmm.2018.3832

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