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miR-760 mediates hypoxia-induced proliferation and apoptosis of human pulmonary artery smooth muscle cells via targeting TLR4

MicroRNAs (miRNAs) have a key role in the pathogenesis of pulmonary arterial hypertension (PAH), a disease characterized by enhanced proliferation and reduced apoptosis of pulmonary artery smooth muscle cells. In the present study, miR-760 was demonstrated to be downregulated in PAH lung tissues com...

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Detalles Bibliográficos
Autores principales: Yang, Yu-Zhong, Zhang, Yun-Feng, Yang, Lei, Xu, Jing, Mo, Xu-Ming, Peng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192785/
https://www.ncbi.nlm.nih.gov/pubmed/30226538
http://dx.doi.org/10.3892/ijmm.2018.3862