Cargando…

miR-760 mediates hypoxia-induced proliferation and apoptosis of human pulmonary artery smooth muscle cells via targeting TLR4

MicroRNAs (miRNAs) have a key role in the pathogenesis of pulmonary arterial hypertension (PAH), a disease characterized by enhanced proliferation and reduced apoptosis of pulmonary artery smooth muscle cells. In the present study, miR-760 was demonstrated to be downregulated in PAH lung tissues com...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yu-Zhong, Zhang, Yun-Feng, Yang, Lei, Xu, Jing, Mo, Xu-Ming, Peng, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192785/ https://www.ncbi.nlm.nih.gov/pubmed/30226538 http://dx.doi.org/10.3892/ijmm.2018.3862

Ejemplares similares

Upregulated miR-17 Regulates Hypoxia-Mediated Human Pulmonary Artery Smooth Muscle Cell Proliferation and Apoptosis by Targeting Mitofusin 2
por: Lu, Zheng, et al.
Publicado: (2016)

miR-760 regulates skeletal muscle proliferation in rheumatoid arthritis by targeting Myo18b
por: Tang, Xujun, et al.
Publicado: (2019)

Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells
por: Zeng, Yan, et al.
Publicado: (2015)

Prognostic role of miR-760 in hepatocellular carcinoma
por: Sun, Dong, et al.
Publicado: (2018)

Plasma miR-601 and miR-760 Are Novel Biomarkers for the Early Detection of Colorectal Cancer
por: Wang, Qifeng, et al.
Publicado: (2012)

Nucleolin Regulates Pulmonary Artery Smooth Muscle Cell Proliferation under Hypoxia by Modulating miRNA Expression
por: Lee, Jihui, et al.
Publicado: (2023)

Effect of miR-29b on the Proliferation and Apoptosis of Pulmonary Artery Smooth Muscle Cells by Targeting Mcl-1 and CCND2
por: Chen, Juan, et al.
Publicado: (2018)

LncRNA CASC2 inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation and migration by regulating the miR-222/ING5 axis
por: Han, Yan, et al.
Publicado: (2020)

MiR‐339 inhibits proliferation of pulmonary artery smooth muscle cell by targeting FGF signaling
por: Chen, Jidong, et al.
Publicado: (2017)

CircYIPF6 regulates glioma cell proliferation, apoptosis, and glycolysis through targeting miR-760 to modulate PTBP1 expression
por: Lei, Dan, et al.
Publicado: (2023)

Endogenous Estrogen Attenuates Hypoxia-Induced Pulmonary Hypertension by Inhibiting Pulmonary Arterial Vasoconstriction and Pulmonary Arterial Smooth Muscle Cells Proliferation
por: Xu, Dunquan, et al.
Publicado: (2013)

Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension
por: Wang, Ai-Ping, et al.
Publicado: (2021)

Mir-206 Regulates Pulmonary Artery Smooth Muscle Cell Proliferation and Differentiation
por: Jalali, Samuel, et al.
Publicado: (2012)

Iptakalim influences the proliferation and apoptosis of human pulmonary artery smooth muscle cells
por: LI, QINGLIN, et al.
Publicado: (2016)

hsa_circWDR37_016 Regulates Hypoxia-Induced Proliferation of Pulmonary Arterial Smooth Muscle Cells
por: Li, Shan-Shan, et al.
Publicado: (2022)

Blockade of JAK2 protects mice against hypoxia‐induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation
por: Zhang, Lei, et al.
Publicado: (2020)

miR-155-5p regulates hypoxia-induced pulmonary artery smooth muscle cell function by targeting PYGL
por: Wang, Guowen, et al.
Publicado: (2022)

MiR-760 enhances sensitivity of pancreatic cancer cells to gemcitabine through modulating Integrin β1
por: Yang, Dejun, et al.
Publicado: (2019)

Hypoxia-induced miR-1260b regulates vascular smooth muscle cell proliferation by targeting GDF11
por: Seong, Minhyeong, et al.
Publicado: (2020)

BMP-2 Up-Regulates PTEN Expression and Induces Apoptosis of Pulmonary Artery Smooth Muscle Cells under Hypoxia
por: Pi, Weifeng, et al.
Publicado: (2012)

Upregulation of miR-760 and miR-186 Is Associated with Replicative Senescence in Human Lung Fibroblast Cells
por: Lee, Young-Hoon, et al.
Publicado: (2014)

Inhibitory effect of Bailing capsule on hypoxia-induced proliferation of rat pulmonary arterial smooth muscle cells
por: Li, Xiaohui, et al.
Publicado: (2016)

Hypoxia promotes cell proliferation by modulating E2F1 in chicken pulmonary arterial smooth muscle cells
por: Yang, Ying, et al.
Publicado: (2013)

MicroRNA-137 Inhibited Hypoxia-Induced Proliferation of Pulmonary Artery Smooth Muscle Cells by Targeting Calpain-2
por: Ge, Xiao-Yue, et al.
Publicado: (2021)

MiR-760 targets HBEGF to control cartilage extracellular matrix degradation in osteoarthritis
por: Zhu, Yingchun, et al.
Publicado: (2023)

Androgen downregulation of miR-760 promotes prostate cancer cell growth by regulating IL6
por: Wang, Shuo, et al.
Publicado: (2020)

MicroRNA-214-3p Regulates Hypoxia-Mediated Pulmonary Artery Smooth Muscle Cell Proliferation and Migration by Targeting ARHGEF12
por: Xing, Xi-Qian, et al.
Publicado: (2019)

miR‐17/20 Controls Prolyl Hydroxylase 2 (PHD2)/Hypoxia‐Inducible Factor 1 (HIF1) to Regulate Pulmonary Artery Smooth Muscle Cell Proliferation
por: Chen, Tianji, et al.
Publicado: (2016)

Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway
por: Gui, Di, et al.
Publicado: (2017)

MiR-328 targeting PIM-1 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in PDGFBB signaling pathway
por: Qian, Zhengjiang, et al.
Publicado: (2016)

The MFF-SIRT1/3 axis, regulated by miR-340-5p, restores mitochondrial homeostasis of hypoxia-induced pulmonary artery smooth muscle cells
por: Huang, Chun-Xia, et al.
Publicado: (2022)

SENP-1 enhances hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells by regulating hypoxia-inducible factor-1α
por: ZHOU, FANG, et al.
Publicado: (2016)

Involvement of miR‐145 in the development of aortic dissection via inducing proliferation, migration, and apoptosis of vascular smooth muscle cells
por: Huang, Wenhui, et al.
Publicado: (2019)

Krüppel-like Factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension
por: Courboulin, Audrey, et al.
Publicado: (2011)

Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells
por: Price, Laura C., et al.
Publicado: (2015)

Role of Rho kinase and Na(+)/H(+) exchange in hypoxia‐induced pulmonary arterial smooth muscle cell proliferation and migration
por: Walker, Jasmine, et al.
Publicado: (2016)

Ubiquitinated AIF is a major mediator of hypoxia-induced mitochondrial dysfunction and pulmonary artery smooth muscle cell proliferation
por: Ma, Cui, et al.
Publicado: (2022)

Emodin inhibits viability, proliferation and promotes apoptosis of hypoxic human pulmonary artery smooth muscle cells via targeting miR-244-5p/DEGS1 axis
por: Yi, Li, et al.
Publicado: (2021)

Upregulation of miR-361-3p suppresses serotonin-induced proliferation in human pulmonary artery smooth muscle cells by targeting SERT
por: Zhang, Ying, et al.
Publicado: (2020)

PDGF mediates pulmonary arterial smooth muscle cell proliferation and migration by regulating NFATc2
por: Zhao, Fang-Yun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_982vdcdb62gcqcb9jloiu640sg