High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In vivo Compared with Monotherapy

PURPOSE: The purpose of the study is to investigate the efficacy of combined treatment with temozolomide (TMZ) and metformin for glioblastoma (GBM) in Vitro and in vivo. MATERIALS AND METHODS: We investigated the efficacy of combined treatment with TMZ and metformin using cell viability and apoptosi...

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Detalles Bibliográficos
Autores principales: Lee, Jung Eun, Lim, Ji Hee, Hong, Yong Kil, Yang, Seung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192919/
https://www.ncbi.nlm.nih.gov/pubmed/29334602
http://dx.doi.org/10.4143/crt.2017.466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192919/
https://www.ncbi.nlm.nih.gov/pubmed/29334602
http://dx.doi.org/10.4143/crt.2017.466

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