DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery

Here we report Digital RNA with pertUrbation of Genes (DRUG-seq), a high-throughput platform for drug discovery. Pharmaceutical discovery relies on high-throughput screening, yet current platforms have limited readouts. RNA-seq is a powerful tool to investigate drug effects using transcriptome chang...

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Detalles Bibliográficos
Autores principales: Ye, Chaoyang, Ho, Daniel J., Neri, Marilisa, Yang, Chian, Kulkarni, Tripti, Randhawa, Ranjit, Henault, Martin, Mostacci, Nadezda, Farmer, Pierre, Renner, Steffen, Ihry, Robert, Mansur, Leandra, Keller, Caroline Gubser, McAllister, Gregory, Hild, Marc, Jenkins, Jeremy, Kaykas, Ajamete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192987/
https://www.ncbi.nlm.nih.gov/pubmed/30333485
http://dx.doi.org/10.1038/s41467-018-06500-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192987/
https://www.ncbi.nlm.nih.gov/pubmed/30333485
http://dx.doi.org/10.1038/s41467-018-06500-x

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