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Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury

Carbon monoxide (CO) can confer protection against cellular stress, whereas the potential involvement of autophagy and lysosomal biogenesis remains incompletely understood. We demonstrate here that the activation of protein kinase R (PKR)-like endoplasmic reticulum (ER) kinase (PERK) with CO increas...

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Detalles Bibliográficos
Autores principales: Kim, Hyo Jeong, Joe, Yeonsoo, Rah, So-Young, Kim, Seul-Ki, Park, Se-Ung, Park, Jeongmin, Kim, Jin, Ryu, Jinhyun, Cho, Gyeong Jae, Surh, Young-Joon, Ryter, Stefan W., Kim, Uh-Hyun, Chung, Hun Taeg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193007/
https://www.ncbi.nlm.nih.gov/pubmed/30333475
http://dx.doi.org/10.1038/s41419-018-1112-x

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