Cargando…
Determining the Quantitative Principles of T Cell Response to Antigenic Disparity in Stem Cell Transplantation
Alloreactivity compromising clinical outcomes in stem cell transplantation is observed despite HLA matching of donors and recipients. This has its origin in the variation between the exomes of the two, which provides the basis for minor histocompatibility antigens (mHA). The mHA presented on the HLA...
Autores principales: | Salman, Ali, Koparde, Vishal, Hall, Charles E., Jameson-Lee, Max, Roberts, Catherine, Serrano, Myrna, AbdulRazzaq, Badar, Meier, Jeremy, Kennedy, Caleb, Manjili, Masoud H., Spellman, Stephen R., Wijesinghe, Dayanjan, Hashmi, Shahrukh, Buck, Greg, Qayyum, Rehan, Neale, Michael, Reed, Jason, Toor, Amir A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193078/ https://www.ncbi.nlm.nih.gov/pubmed/30364159 http://dx.doi.org/10.3389/fimmu.2018.02284 |
Ejemplares similares
-
Dynamical system modeling to simulate donor T cell response to whole exome sequencing-derived recipient peptides: Understanding randomness in alloreactivity incidence following stem cell transplantation
por: Koparde, Vishal, et al.
Publicado: (2017) -
Stem Cell Transplantation as a Dynamical System: Are Clinical Outcomes Deterministic?
por: Toor, Amir A., et al.
Publicado: (2014) -
In silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem-Cell Transplant Donors and Recipients: Understanding the Quantitative Immunobiology of Allogeneic Transplantation
por: Jameson-Lee, Max, et al.
Publicado: (2014) -
Sequence homology between HLA-bound cytomegalovirus and human peptides: A potential trigger for alloreactivity
por: Hall, Charles E., et al.
Publicado: (2017) -
A Preliminary Investigation towards the Risk Stratification of Allogeneic Stem Cell Recipients with Respect to the Potential for Development of GVHD via Their Pre-Transplant Plasma Lipid and Metabolic Signature
por: Contaifer, Daniel, et al.
Publicado: (2019)