MicroRNA-212-5p Prevents Dopaminergic Neuron Death by Inhibiting SIRT2 in MPTP-Induced Mouse Model of Parkinson’s Disease

Recently, emerging evidences show that sirtuins (SIRTs) modulate aging progress and affect neurodegenerative diseases. For example, inhibition of SIRT2 has been recognized to exert neuroprotective effects in Parkinson’s disease (PD). However, current SIRT2 inhibitors are lack of selective property d...

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Detalles Bibliográficos
Autores principales: Sun, Sifan, Han, Xiaojuan, Li, Xueting, Song, Qiqi, Lu, Ming, Jia, Miaomiao, Ding, Jianhua, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193094/
https://www.ncbi.nlm.nih.gov/pubmed/30364275
http://dx.doi.org/10.3389/fnmol.2018.00381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193094/
https://www.ncbi.nlm.nih.gov/pubmed/30364275
http://dx.doi.org/10.3389/fnmol.2018.00381

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