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The Leptomeninges Produce Prostaglandin D(2) Involved in Sleep Regulation in Mice

Injection of nanomolar amounts of prostaglandin D(2) (PGD(2)) into the rat brain has dose and time-dependent somnogenic effects, and the PGD(2)-induced sleep is indistinguishable from physiologic sleep. Sleep-inducing PGD(2) is produced in the brain by lipocalin-type PGD(2) synthase (LPGDS). Three p...

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Detalles Bibliográficos
Autores principales:	Cherasse, Yoan, Aritake, Kosuke, Oishi, Yo, Kaushik, Mahesh K., Korkutata, Mustafa, Urade, Yoshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193105/ https://www.ncbi.nlm.nih.gov/pubmed/30364224 http://dx.doi.org/10.3389/fncel.2018.00357

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