Cargando…

Altered Synaptic and Extrasynaptic NMDA Receptor Properties in Substantia Nigra Dopaminergic Neurons From Mice Lacking the GluN2D Subunit

N-methyl-D-aspartate receptors (NMDARs) are ubiquitously expressed in the mammalian brain and are essential for neuronal development, survival and plasticity. GluN2 subunit composition has a profound effect on the properties of NMDARs. In substantia nigra dopaminergic (SNc-DA) neurons, pharmacologic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morris, Paul G., Mishina, Masayoshi, Jones, Susan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193106/ https://www.ncbi.nlm.nih.gov/pubmed/30364232 http://dx.doi.org/10.3389/fncel.2018.00354

Ejemplares similares

Mg(2+) block properties of triheteromeric GluN1–GluN2B–GluN2D NMDA receptors on neonatal rat substantia nigra pars compacta dopaminergic neurones
por: Huang, Zhuo, et al.
Publicado: (2014)

Mechanisms regulating spill‐over of synaptic glutamate to extrasynaptic NMDA receptors in mouse substantia nigra dopaminergic neurons
por: Wild, A. R., et al.
Publicado: (2015)

Activity-dependent regulation of NMDA receptors in substantia nigra dopaminergic neurones
por: Wild, Angela R, et al.
Publicado: (2014)

Open-channel blockade is less effective on GluN3B than GluN3A subunit-containing NMDA receptors
por: McClymont, David W., et al.
Publicado: (2012)

Cognitive Impairment That Is Induced by (R)-Ketamine Is Abolished in NMDA GluN2D Receptor Subunit Knockout Mice
por: Ide, Soichiro, et al.
Publicado: (2019)

Subunit Arrangement and Phenylethanolamine Binding in GluN1/GluN2B NMDA Receptors
por: Karakas, Erkan, et al.
Publicado: (2011)

Essential Role of NMDA Receptor Channel ε4 Subunit (GluN2D) in the Effects of Phencyclidine, but Not Methamphetamine
por: Hagino, Yoko, et al.
Publicado: (2010)

GluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity
por: Shipton, Olivia A., et al.
Publicado: (2014)

GluN2D-containing NMDA receptors-mediate synaptic currents in hippocampal interneurons and pyramidal cells in juvenile mice
por: von Engelhardt, Jakob, et al.
Publicado: (2015)

Influence of GluN2 subunit identity on NMDA receptor function
por: Wyllie, D.J.A., et al.
Publicado: (2013)

NMDA receptor GluN2A/GluN2B subunit ratio as synaptic trait of levodopa-induced dyskinesias: from experimental models to patients
por: Mellone, Manuela, et al.
Publicado: (2015)

Local constraints in either the GluN1 or GluN2 subunit equally impair NMDA receptor pore opening
por: Talukder, Iehab, et al.
Publicado: (2011)

GluN1 and GluN2A NMDA Receptor Subunits Increase in the Hippocampus during Memory Consolidation in the Rat
por: Cercato, Magali C., et al.
Publicado: (2017)

DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease
por: Schmidt, Mandi E., et al.
Publicado: (2020)

Rapid homeostatic downregulation of LTP by extrasynaptic GluN2B receptors
por: Delgado, Jary Y., et al.
Publicado: (2018)

Allosteric modulation of GluN1/GluN3 NMDA receptors by GluN1-selective competitive antagonists
por: Rouzbeh, Nirvan, et al.
Publicado: (2023)

Identification of homologous GluN subunits variants accelerates GRIN variants stratification
por: Santos-Gómez, Ana, et al.
Publicado: (2022)

Astrocytes increase the activity of synaptic GluN2B NMDA receptors
por: Hahn, Junghyun, et al.
Publicado: (2015)

GluN3A: An NMDA Receptor Subunit with Exquisite Properties and Functions
por: Kehoe, Laura A., et al.
Publicado: (2013)

Potential Roles for the GluN2D NMDA Receptor Subunit in Schizophrenia
por: Vinnakota, Chitra, et al.
Publicado: (2023)

Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
por: Grand, Teddy, et al.
Publicado: (2018)

GluN2A Subunit-Containing NMDA Receptors Are the Preferential Neuronal Targets of Homocysteine
por: Sibarov, Dmitry A., et al.
Publicado: (2016)

Common synaptic phenotypes arising from diverse mutations in the human NMDA receptor subunit GluN2A
por: Elmasri, Marwa, et al.
Publicado: (2022)

The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B
por: Tsang, Ka Hing, et al.
Publicado: (2014)

Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors
por: Skrenkova, Kristyna, et al.
Publicado: (2019)

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences
por: McKay, Sean, et al.
Publicado: (2018)

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis
por: Üner, Aykut, et al.
Publicado: (2015)

GluN2 Subunit-Dependent Redox Modulation of NMDA Receptor Activation by Homocysteine
por: Sibarov, Dmitry A., et al.
Publicado: (2020)

Synaptic GluN2A-Containing NMDA Receptors: From Physiology to Pathological Synaptic Plasticity
por: Franchini, Luca, et al.
Publicado: (2020)

Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice
por: Gajardo, Ivana, et al.
Publicado: (2018)

Age-Dependent, Subunit Specific Action of Hydrogen Sulfide on GluN1/2A and GluN1/2B NMDA Receptors
por: Yakovlev, Aleksey V., et al.
Publicado: (2017)

The NMDA Receptor Subunit (GluN1 and GluN2A) Modulation Following Different Conditions of Cocaine Abstinence in Rat Brain Structures
por: Smaga, Irena, et al.
Publicado: (2021)

The GluN2A Subunit Regulates Neuronal NMDA receptor-Induced Microglia-Neuron Physical Interactions
por: Eyo, Ukpong B., et al.
Publicado: (2018)

GluN2A and GluN2B NMDA receptors use distinct allosteric routes
por: Tian, Meilin, et al.
Publicado: (2021)

Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors
por: Zeng, Yue, et al.
Publicado: (2022)

Palmitoylation at Two Cysteine Clusters on the C-Terminus of GluN2A and GluN2B Differentially Control Synaptic Targeting of NMDA Receptors
por: Mattison, Hayley A., et al.
Publicado: (2012)

Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes
por: Shelkar, Gajanan P., et al.
Publicado: (2019)

An Alternating GluN1-2-1-2 Subunit Arrangement in Mature NMDA Receptors
por: Riou, Morgane, et al.
Publicado: (2012)

The Extracellular Domains of GluN Subunits Play an Essential Role in Processing NMDA Receptors in the ER
por: Horak, Martin, et al.
Publicado: (2021)

Activation of excitatory glycine NMDA receptors: At the mercy of a whimsical GluN1 subunit
por: He, Miaomiao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_asd2lamv52ue4u3da55nqb821s