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Substrate Specificity Analysis of Dihydrofolate/Dihydromethanopterin Reductase Homologs in Methylotrophic α-Proteobacteria

Methane-producing archaea and methylotrophic bacteria use tetrahydromethanopterin (H(4)MPT) and/or tetrahydrofolate (H(4)F) as coenzymes in one-carbon (C1) transfer pathways. The α-proteobacterium Methylobacterium extorquens AM1 contains a dihydromethanopterin reductase (DmrA) and two annotated dihy...

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Detalles Bibliográficos
Autores principales: Burton, Mark, Abanobi, Chidinma, Wang, Kate Tzu-Chi, Ma, Yihua, Rasche, Madeline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193120/
https://www.ncbi.nlm.nih.gov/pubmed/30364315
http://dx.doi.org/10.3389/fmicb.2018.02439