Holo-Seq: single-cell sequencing of holo-transcriptome

Current single-cell RNA-seq approaches are hindered by preamplification bias, loss of strand of origin information, and the inability to observe small-RNA and mRNA dual transcriptomes. Here, we introduce a single-cell holo-transcriptome sequencing (Holo-Seq) that overcomes all three hurdles. Holo-Se...

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Detalles Bibliográficos
Autores principales: Xiao, Zhengyun, Cheng, Guo, Jiao, Yang, Pan, Chen, Li, Ran, Jia, Danmei, Zhu, Jing, Wu, Chao, Zheng, Min, Jia, Junling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193298/
https://www.ncbi.nlm.nih.gov/pubmed/30333049
http://dx.doi.org/10.1186/s13059-018-1553-7

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