Synthesis of Nepetoidin B

The first synthesis of nepetoidin B in an overall yield of 17% was achieved in two steps through Baeyer–Villiger oxidation of commercially available 1,5-bis(3,4-dimethoxyphenyl)-1,4-pentadien-3-one with oxone to produce the tetramethylated nepetoidin B, followed by demethylation using boron tribromi...

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Autores principales: Timokhin, Vitaliy, Regner, Matthew, Tsuji, Yukiko, Grabber, John, Ralph, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193368/
http://dx.doi.org/10.1055/s-0036-1591556
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author Timokhin, Vitaliy
Regner, Matthew
Tsuji, Yukiko
Grabber, John
Ralph, John
author_facet Timokhin, Vitaliy
Regner, Matthew
Tsuji, Yukiko
Grabber, John
Ralph, John
author_sort Timokhin, Vitaliy
collection PubMed
description The first synthesis of nepetoidin B in an overall yield of 17% was achieved in two steps through Baeyer–Villiger oxidation of commercially available 1,5-bis(3,4-dimethoxyphenyl)-1,4-pentadien-3-one with oxone to produce the tetramethylated nepetoidin B, followed by demethylation using boron tribromide.
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spelling pubmed-61933682018-10-30 Synthesis of Nepetoidin B Timokhin, Vitaliy Regner, Matthew Tsuji, Yukiko Grabber, John Ralph, John Synlett The first synthesis of nepetoidin B in an overall yield of 17% was achieved in two steps through Baeyer–Villiger oxidation of commercially available 1,5-bis(3,4-dimethoxyphenyl)-1,4-pentadien-3-one with oxone to produce the tetramethylated nepetoidin B, followed by demethylation using boron tribromide. © Georg Thieme Verlag 2018-06-01 2018-03-28 /pmc/articles/PMC6193368/ http://dx.doi.org/10.1055/s-0036-1591556 Text en © Thieme Medical Publishers
spellingShingle Timokhin, Vitaliy
Regner, Matthew
Tsuji, Yukiko
Grabber, John
Ralph, John
Synthesis of Nepetoidin B
title Synthesis of Nepetoidin B
title_full Synthesis of Nepetoidin B
title_fullStr Synthesis of Nepetoidin B
title_full_unstemmed Synthesis of Nepetoidin B
title_short Synthesis of Nepetoidin B
title_sort synthesis of nepetoidin b
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193368/
http://dx.doi.org/10.1055/s-0036-1591556
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