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Display of the HIV envelope protein at the yeast cell surface for immunogen development
As a step toward the development of variant forms of Env with enhanced immunogenic properties, we have expressed the glycoprotein in the yeast surface display system in a form that can be subjected to random mutagenesis followed by screening for forms with enhanced binding to germline antibodies. To...
Autores principales: | Mathew, Elizabeth, Zhu, Hong, Connelly, Sara M., Sullivan, Mark A., Brewer, Matthew G., Piepenbrink, Michael S., Kobie, James J., Dewhurst, Stephen, Dumont, Mark E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193675/ https://www.ncbi.nlm.nih.gov/pubmed/30335821 http://dx.doi.org/10.1371/journal.pone.0205756 |
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