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Independent amplification of co-infected long incubation period low conversion efficiency prion strains
Prion diseases are caused by a misfolded isoform of the prion protein, PrP(Sc). Prion strains are hypothesized to be encoded by strain-specific conformations of PrP(Sc) and prions can interfere with each other when a long-incubation period strain (i.e. blocking strain) inhibits the conversion of a s...
Autores principales: | Eckland, Thomas E., Shikiya, Ronald A., Bartz, Jason C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193734/ https://www.ncbi.nlm.nih.gov/pubmed/30335854 http://dx.doi.org/10.1371/journal.ppat.1007323 |
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