Recombination hotspots in an extended human pseudoautosomal domain predicted from double-strand break maps and characterized by sperm-based crossover analysis

The human X and Y chromosomes are heteromorphic but share a region of homology at the tips of their short arms, pseudoautosomal region 1 (PAR1), that supports obligate crossover in male meiosis. Although the boundary between pseudoautosomal and sex-specific DNA has traditionally been regarded as con...

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Detalles Bibliográficos
Autores principales: Poriswanish, Nitikorn, Neumann, Rita, Wetton, Jon H., Wagstaff, John, Larmuseau, Maarten H. D., Jobling, Mark A., May, Celia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193736/
https://www.ncbi.nlm.nih.gov/pubmed/30296256
http://dx.doi.org/10.1371/journal.pgen.1007680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193736/
https://www.ncbi.nlm.nih.gov/pubmed/30296256
http://dx.doi.org/10.1371/journal.pgen.1007680

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