Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils

Parasitic nematodes produce an unusual class of fatty acid and retinol (FAR)-binding proteins that may scavenge host fatty acids and retinoids. Two FARs from Brugia malayi (Bm-FAR-1 and Bm-FAR-2) were expressed as recombinant proteins, and their ligand binding, structural characteristics, and immuno...

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Detalles Bibliográficos
Autores principales: Zhan, Bin, Arumugam, Sridhar, Kennedy, Malcolm W., Tricoche, Nancy, Lian, Lu-Yun, Asojo, Oluwatoyin A., Bennuru, Sasisekhar, Bottazzi, Maria Elena, Hotez, Peter J., Lustigman, Sara, Klei, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193737/
https://www.ncbi.nlm.nih.gov/pubmed/30296268
http://dx.doi.org/10.1371/journal.pntd.0006772

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