Cargando…

Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking

Glycogen metabolism commonly altered in cancer is just beginning to be understood. Phosphoglucomutase 1 (PGM1), the first enzyme in glycogenesis that catalyzes the reversible conversion between glucose 1-phosphate (G-1-P) and glucose 6-phosphate (G-6-P), participates in both the breakdown and synthe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Guang-Zhi, Zhang, Yajuan, Cong, Wen-Ming, Wu, Xueyuan, Wang, Xiongjun, Wu, Siyang, Wang, Siyao, Zhou, Weiping, Yuan, Shengxian, Gao, Hong, Yu, Guanzhen, Yang, Weiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193743/ https://www.ncbi.nlm.nih.gov/pubmed/30335765 http://dx.doi.org/10.1371/journal.pbio.2006483

Ejemplares similares

Phosphoglucomutase comes into the spotlight
por: Doello, Sofía, et al.
Publicado: (2023)

Role of phosphoglucomutase in regulating trehalose metabolism in Nilaparvata lugens
por: Pan, Bi-Ying, et al.
Publicado: (2020)

Phosphoglucomutase Is Not the Target for Galactose Toxicity in Plants
por: Althammer, Martina, et al.
Publicado: (2020)

Limitations of galactose therapy in phosphoglucomutase 1 deficiency
por: Nolting, Kristine, et al.
Publicado: (2017)

The Glaesserella parasuis phosphoglucomutase is partially required for lipooligosaccharide synthesis
por: Feng, Saixiang, et al.
Publicado: (2020)

Production and crystallization of α-phosphoglucomutase from Lactococcus lactis. Corrigendum
por: Nogly, Przemyslaw, et al.
Publicado: (2013)

Phosphoglucomutase 1 contributes to optimal cyst development in Toxoplasma gondii
por: Quach, Emily V., et al.
Publicado: (2022)

Plastidic phosphoglucomutase and ADP-glucose pyrophosphorylase mutants impair starch synthesis in rice pollen grains and cause male sterility
por: Lee, Sang-Kyu, et al.
Publicado: (2016)

Polymorphisme de la phosphoglucomutase (PGM) dans l'espèce bovine
por: Ansay, M, et al.
Publicado: (1971)

Two Phosphoglucomutase Paralogs Facilitate Ionophore-Triggered Secretion of the Toxoplasma Micronemes
por: Saha, Sudeshna, et al.
Publicado: (2017)

Implication of Potential Differential Roles of the Two Phosphoglucomutase Isoforms in the Protozoan Parasite Cryptosporidium parvum
por: Nie, Jiawen, et al.
Publicado: (2021)

Isoenzymes of hexokinase, 6-phosphogluconate dehydrogenase, phosphoglucomutase and lactate dehydrogenase in uterine cancer.
por: Marshall, M. J., et al.
Publicado: (1979)

Evaluation of Entamoeba histolytica recombinant phosphoglucomutase protein for serodiagnosis of amoebic liver abscess
por: Ning, Tan Zi, et al.
Publicado: (2013)

Constitutive homologous expression of phosphoglucomutase and transaldolase increases the metabolic flux of Fusarium oxysporum
por: Anasontzis, George E, et al.
Publicado: (2014)

CT295 Is Chlamydia trachomatis’ Phosphoglucomutase and a Type 3 Secretion Substrate
por: Triboulet, Sébastien, et al.
Publicado: (2022)

Successful heart transplantation in an infant with phosphoglucomutase 1 deficiency (PGM1‐CDG)
por: Altassan, Ruqaiah, et al.
Publicado: (2022)

Phosphoglucomutase is absent in Trypanosoma brucei and redundantly substituted by phosphomannomutase and phospho-N-acetylglucosamine mutase
por: Bandini, Giulia, et al.
Publicado: (2012)

Inactivation of the phosphoglucomutase gene pgm in Corynebacterium glutamicum affects cell shape and glycogen metabolism
por: Seibold, Gerd M., et al.
Publicado: (2013)

Sequence-structure relationships, expression profiles, and disease-associated mutations in the paralogs of phosphoglucomutase 1
por: Muenks, Andrew G., et al.
Publicado: (2017)

Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis
por: Yan, Kaizhou, et al.
Publicado: (2022)

Plastidial Phosphoglucomutase (pPGM) Overexpression Increases the Starch Content of Transgenic Sweet Potato Storage Roots
por: Wang, Yannan, et al.
Publicado: (2022)

Stress response requires an efficient connection between glycogen and central carbon metabolism by phosphoglucomutases in cyanobacteria
por: Ortega-Martínez, Pablo, et al.
Publicado: (2022)

Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM
por: Pathania, Monisha, et al.
Publicado: (2021)

Reduction of the Cytosolic Phosphoglucomutase in Arabidopsis Reveals Impact on Plant Growth, Seed and Root Development, and Carbohydrate Partitioning
por: Malinova, Irina, et al.
Publicado: (2014)

Structure and Characterization of Phosphoglucomutase 5 from Atlantic and Baltic Herring—An Inactive Enzyme with Intact Substrate Binding
por: Gustafsson, Robert, et al.
Publicado: (2020)

miR-1293 acts as a tumor promotor in lung adenocarcinoma via targeting phosphoglucomutase 5
por: Chen, Bing, et al.
Publicado: (2021)

Identification, Characteristics and Function of Phosphoglucomutase (PGM) in the Agar Biosynthesis and Carbon Flux in the Agarophyte Gracilariopsis lemaneiformis (Rhodophyta)
por: Chen, Qionglin, et al.
Publicado: (2022)

Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono-, Di-, and Trifluorinated d-Gluco-heptuloses by Glucokinase: Tunable Phosphoglucomutase Inhibition
por: Zhu, Jian-She, et al.
Publicado: (2019)

Down-regulation of phosphoglucomutase 3 mediates sulforaphane-induced cell death in LNCaP prostate cancer cells
por: Lee, Chan-Hee, et al.
Publicado: (2010)

Genetically-Determined Polymorphism of Nonspecific Esterases and Phosphoglucomutase in Eight Introduced Breeds of the Silkworm, Bombyx mori, Raised in Bulgaria
por: Staykova, Teodora
Publicado: (2008)

Isolation, identification, and biochemical characterization of a novel bifunctional phosphomannomutase/phosphoglucomutase from the metagenome of the brown alga Laminaria digitata
por: Jackson, Stephen A., et al.
Publicado: (2022)

CircGNG4 Promotes the Progression of Prostate Cancer by Sponging miR-223 to Enhance EYA3/c-myc Expression
por: Xu, Shengxian, et al.
Publicado: (2021)

Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects
por: Shang, Run-Ze, et al.
Publicado: (2016)

Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene
por: Lundin, Karin E., et al.
Publicado: (2015)

Long-term monitoring and analysis of the longitudinal differential settlement of an expressway bridge–subgrade transition section in a loess area
por: Du, Yang, et al.
Publicado: (2022)

Neuraminidase 1 (NEU1) promotes proliferation and migration as a diagnostic and prognostic biomarker of hepatocellular carcinoma
por: Hou, Guojun, et al.
Publicado: (2016)

Integrin Trafficking and Tumor Progression
por: Shin, Sejeong, et al.
Publicado: (2012)

Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-d-phosphohexomutase superfamily
por: Backe, Paul Hoff, et al.
Publicado: (2020)

Proline-rich protein 11 overexpression is associated with a more aggressive phenotype and poor overall survival in ovarian cancer patients
por: Zhan, Yu, et al.
Publicado: (2020)

EYA4 serves as a prognostic biomarker in hepatocellular carcinoma and suppresses tumour angiogenesis and metastasis
por: Gu, Fangming, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dnn0c35n3g7d5dslq1lltgvp8o