Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development

Malaria infection during pregnancy, caused by the sequestering of Plasmodium falciparum parasites in the placenta, leads to high infant mortality and maternal morbidity. The parasite-placenta adherence mechanism is mediated by the VAR2CSA protein, a target for natural occurring immunity. Currently,...

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Detalles Bibliográficos
Autores principales: Benavente, Ernest Diez, Oresegun, Damilola R., de Sessions, Paola Florez, Walker, Eloise M., Roper, Cally, Dombrowski, Jamille G., de Souza, Rodrigo M., Marinho, Claudio R. F., Sutherland, Colin J., Hibberd, Martin L., Mohareb, Fady, Baker, David A., Clark, Taane G., Campino, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193930/
https://www.ncbi.nlm.nih.gov/pubmed/30337594
http://dx.doi.org/10.1038/s41598-018-33767-3

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