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Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis

Genomic studies of Mycobacterium tuberculosis bacteria have revealed loci associated with resistance to anti-tuberculosis drugs. However, the molecular consequences of polymorphism within these candidate loci remain poorly understood. To address this, we have used computational tools to quantify the...

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Detalles Bibliográficos
Autores principales:	Portelli, Stephanie, Phelan, Jody E., Ascher, David B., Clark, Taane G., Furnham, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193939/ https://www.ncbi.nlm.nih.gov/pubmed/30337649 http://dx.doi.org/10.1038/s41598-018-33370-6

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