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Massive expression of germ cell-specific genes is a hallmark of cancer and a potential target for novel treatment development

Cancer cells have been found to frequently express genes that are normally restricted to the testis, often referred to as cancer/testis (CT) antigens or genes. Because germ cell-specific antigens are not recognized as “self” by the innate immune system, CT-genes have previously been suggested as ide...

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Detalles Bibliográficos
Autores principales: Bruggeman, Jan Willem, Koster, Jan, Lodder, Paul, Repping, Sjoerd, Hamer, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193945/
https://www.ncbi.nlm.nih.gov/pubmed/29907769
http://dx.doi.org/10.1038/s41388-018-0357-2

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