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The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactions

14-3-3 proteins are a family of structurally similar phospho-binding proteins that regulate essentially every major cellular function. Decades of research on 14-3-3s have revealed a remarkable network of interacting proteins that demonstrate how 14-3-3s integrate and control multiple signaling pathw...

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Detalles Bibliográficos
Autores principales: Pennington, KL, Chan, TY, Torres, MP, Andersen, JL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193947/
https://www.ncbi.nlm.nih.gov/pubmed/29915393
http://dx.doi.org/10.1038/s41388-018-0348-3