Cargando…

Intra- and inter-protein couplings of backbone motions underlie protein thiol-disulfide exchange cascade

The thioredoxin (Trx)-coupled arsenate reductase (ArsC) is a family of enzymes that catalyzes the reduction of arsenate to arsenite in the arsenic detoxification pathway. The catalytic cycle involves a series of relayed intramolecular and intermolecular thiol-disulfide exchange reactions. Structures...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wenbo, Niu, Xiaogang, Ding, Jienv, Hu, Yunfei, Jin, Changwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193951/
https://www.ncbi.nlm.nih.gov/pubmed/30337655
http://dx.doi.org/10.1038/s41598-018-33766-4